Staph Lab

Quorum Sensing

Quorum-sensing and biofilm interactions

biofilm formationMy group’s interest in S. aureus quorum-sensing lead us into biofilm studies on this important pathogen. We determined that the quorum-sensing system activates a biofilm dispersal pathway, and follow-up studies identified the cysteine proteases (Staphopains) as being the important end products of this pathway. Currently, we are investigating the targets of Staphopains in the S. aureus biofilm matrix.

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Horswill Laboratory, University of Colorado.

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Lab Info
Research Complex 1 North
12800 E. 19th Ave., Rm. P18-9101

Alexandar Horswill, PhD
Professor of Immunology and Microbiology

(303) 724-3534
alexander.horswill@ucdenver.edu